Postdoctoral Fellow, Mechatronic Engineering for Immunology

BioHub
Chicago, IL (Onsite)Posted 12 March 2026

Tech Stack

Job Description

Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health. The Team Our decoding inflammation team builds tools to enable precise molecular-level measurements of inflammation within human tissues in real time, and develop proactive, early interventions that can be deployed when inflammation — which underlies the most significant causes of death worldwide — first flares in the body. You can learn more about our work here . Our team collaborates with three powerhouse universities - Northwestern University, the University of Chicago, and the University of Illinois Urbana-Champaign - to develop first-in-class technologies and make breakthroughs. Our Vision Pursue large scientific challenges that cannot be pursued in conventional environments Enable individual investigators to pursue their riskiest and most innovative ideas Facilitate research by scientists and clinicians at our home institutions and beyond We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease. The Opportunity We are seeking exceptional early-career scientists with backgrounds in mechatronics, robotics, microfabrication, or related engineering disciplines to join our growing group as a Postdoctoral Fellow. The ideal candidate will have experience working with engineered experimental systems and living cells, and will be motivated to contribute hands-on to the development of a highly interdisciplinary research platform. What You'll Do Develop and operate components of an experimental platform, including microfabricated devices, script-based liquid handling, and/or 6DOF robotic modules, to study how temporal microenvironments influence immune cell fate decisions Conduct quantitative validation studies to characterize system performance (e.g., timing precision, crosstalk, stability) Execute and support cell-based experiments within engineered systems, with attention to viability, timing, and reproducibility Collaborate across disciplines with colleagues in engineering, imaging, data science, and immunology Contribute to the documentation, dissemination, and reproducibility of platform methods and experimental workflows Uphold the Biohub’s values of open science, teamwork, and scholarly excellence What You'll Bring Essential - PhD (or equivalent) in engineering (e.g., mechatronics, robotics, bioengineering, mechanical engineering, microfabrication, or related fields), with 0-3 years of postdoctoral or equivalent research experience. 3+ years of experience in mechatronics and robotic systems 3+ years of experience with scientific programming or scripting (e.g., Python, MATLAB) for experiment execution or analysis Understanding of hands-on building, system validation, stress-testing, or scaling experimental platforms Nice to have - Familiarity with PCB design 2+ years of photolithography experience Familiarity with wet bench Surface functionalization experience Experience interfacing experimental systems with data analysis or ML workflows Compensation The Chicago, IL base pay for a new hire in this role is $84,150. Benefits for the Whole You We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. Provides a generous employer match on employee 401(k) ... (truncated, view full listing at source)
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