Senior Vice President, AI & Digital Platform

ABOUT PIONEERING INTELLIGENCE Pioneering Intelligence builds on Flagship Pioneering’s legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms breakthrough ideas into world-changing companies, elevating the AI advances happening across the ecosystem in human health, sustainability, and beyond. THE ROLE The Pioneering Intelligence team at Flagship Pioneering builds the digital and AI foundation that accelerates the creation and growth our companies. We are seeking a Senior Vice President (SVP) – AI Digital Platform to enable AI tooling across our enterprise, shepherd our AI-native data platform, maintain and evolve the digital backbone of our early stage companies, and lead a world-class technology team though support, empowerment, and accountability. This is a senior leadership role within the Pioneering Intelligence Initiative, offering the opportunity to shape the strategy, execution, and impact of AI across Flagship’s ecosystem. As the SVP – AI Digital Platform , you will be responsible for defining and executing the vision for how AI and digital technologies enable Flagship and its portfolio companies. You will shepherd and deliver the platforms, tools, and infrastructure that power AI-native operations and empower scientific and business teams. This role combines strategic leadership with deep technical expertise, requiring you to operate in highly ambiguous environments, shape long-term direction, and build organizational capabilities that endure. KEY RESPONSIBILITIES Enable AI tooling and capabilities across scientific and operational workflows. Architect and implement an AI-native data platform that empowers Agentic AI and AI Modeling teams. Maintain and evolve the PI Digital Backbone—Flagship’s shared infrastructure “starter kit” for new company launches, including compute, shared code, and AI tools. Support and develop a high-performing, product-minded technology organization. Partner with portfolio company founders, venture teams, scientific leaders, and functional teams to align and drive adoption of our shared digital strategy. Develop and communicate strategy for Flagship’s AI initiatives internally and externally. PROFESSIONAL EXPERIENCE QUALIFICATIONS 15+ years of progressive leadership experience in AI, data platforms, or digital technology, ideally spanning both technology and life sciences. Demonstrated success in building and scaling platforms that deliver measurable scientific or business outcomes. Deep expertise in AI, ML, and data architectures, paired with strong product and business acumen. Proven ability to thrive in highly ambiguous, rapidly evolving environments. Track record of building and leading diverse, high-performing teams. Excellent communication and collaboration skills, with the ability to influence at all levels of an organization. Preferred Qualifications Experience creating or scaling digital platforms in complex or scientific domains. Familiarity with life sciences RD workflows and the opportunities for AI-driven acceleration. Experience with early-stage B2B software product development. Strong network within the AI and digital innovation ecosystem. WHY PIONEERING INTELLIGENCE? Lead a bold initiative at the intersection of AI, digital platforms, and pioneering science. Help define the future of Flagship’s digital and AI strategy, impacting multiple portfolio companies. Collaborate with visionary founders, scientists, and innovators across Flagship’s ecosystem. Build in a supportive, mission-driven culture with access to world-class technical and operational resources. Competitive compensation and benefits, including equity, commensurate with experience. ABOUT FLAGSHIP PIONEERING Flagship Pioneering invents ... (truncated, view full listing at source)