Senior Linux Systems Engineer
Ultima GenomicsFremont, California, United StatesPosted 19 March 2026
Job Description
Rapidly Growing Life Sciences Technology Company
Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.
We are looking for a highly motivated Senior Linux Systems Engineer to join our Computing Team!
You will work on high-performance computing (HPC) systems that are part of our sequencing platform. The ideal candidate is a hands-on Linux expert who thrives on optimizing performance and building secure, scalable and reliable systems in a fast-paced environment.
This is a full-time, on-site position at our Fremont, CA headquarters.
How You’ll Contribute
Design, build, and maintain high-performance Linux systems supporting compute and data-intensive workloads
Optimize system performance through kernel and filesystem tuning; identify and eliminate I/O, memory, or network bottlenecks
Automate provisioning and configuration management using orchestration tools such as Ansible and Salt
Monitor and troubleshoot kernel, driver, and hardware issues; perform root cause analysis in partnership with data and engineering teams and propose long-term solutions
Ensure system reliability through regular patching, monitoring, and performance tuning
Maintain accurate system documentation, runbooks, and configuration baselines
Collaborate with software, hardware, and scientific teams to ensure platform reliability and scalability
Other duties as assigned
Qualifications, Skills, Knowledge Abilities
BS in Computer Science, Engineering, or related field
5+ years of experience designing and building high-performance physical Linux systems in high-throughput or mission-critical environments
Deep knowledge of Linux kernel, NFS and Linux file system performance tuning
Solid background in TCP/IP networking, routing, VLANs, and firewall rules
Experience with the latest CPU and GPU technologies
Proficiency in shell scripting (bash), working knowledge of Python, and familiarity with Ansible or similar configuration management tools
Proven hands-on experience building servers from components, diagnosing hardware failures, and working with vendors
Excellent documentation and communication skills
May occasionally be exposed to activity that requires pulling/lifting/moving/carrying up to 50 lbs
Experience with cloud computing infrastructure (e.g. AWS) and Docker desirable
Familiarity with security frameworks and compliance standards (e.g. ISO 27001) a plus
At Ultima Genomics, your base pay is one part of your total compensation package. This role pays between $125,000
and
$150,000, if performed in California, and your actual base pay will depend on your skills, qualifications, experience, and location. Please note that the compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits. This role is also eligible for a competitive benefits package that includes: medical, dental, vision, life, and disability insurance; 401(k) retirement plan; flexible spending health savings account; paid holidays; ... (truncated, view full listing at source)
Apply Now
Direct link to company career page
AI Resume Fit Check
See exactly which skills you match and which are missing before you apply. Free, instant, no spam.
Check my resume fitFree · No credit card
More jobs at Ultima Genomics
See all →Engineering Intern
Fremont, California, United States · 19 March 2026
Field Service Engineer I, Development Program
Fremont, California, United States · 19 March 2026
Field Service Engineer II, UAE
Abu Dhabi, United Arab Emirates · 19 March 2026
Associate Strategic Accounts Director, Pharma and Biotech
Remote US · 19 March 2026