Capability Manager, Business Applications

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three RD sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Capability Manager, Business Applications as part of the IT team based in Somerset, NJ . Role Overview The IT Manager – Business Applications is a technically strong individual contributor responsible for partnering with business functions and enabling the successful delivery, enhancement, and support of enterprise applications across corporate domains including Finance, Procurement, Commercial, and other business functions as needed. Reporting to the Lead, Business Applications, this role owns end-to-end system capabilities including configuration, integration, support, and continuous improvement. The role bridges technical execution with strategic planning, driving project delivery in collaboration with cross-functional stakeholders including business teams, enterprise architecture, cybersecurity, vendors, and auditors. The ideal candidate brings deep technical expertise, strong business partnership skills, and a forward-looking mindset toward innovation, scalability, compliance, and lifecycle management across a diverse application landscape. Key Responsibilities Serve as the IT business enablement lead for Business Applications spanning Finance, Procurement, Commercial, and other corporate functions, leveraging platforms such as SAP S/4HANA, SAP BTP, SAP Ariba, Anaplan, and other enterprise or SaaS solutions. Lead configuration, administration, and continuous improvement of applications with a focus on scalability, integration, automation, and user experience. Partner with business stakeholders to understand requirements and translate them into robust, scalable, and compliant technology solutions. Design, implement, and maintain secure integrations between enterprise systems and internal/external applications, ensuring data integrity and seamless process flow. Provide advanced Tier 2/3 application support, coordinating with managed service providers and vendors to ensure SLA adherence and continuous service improvement. Lead testing strategies including system integration testing, UAT, regression testing, and release/cutover planning for system upgrades and enhancements. Monitor system performance, availability, and data quality; proactively identify and drive improvements, optimization opportunities, and technical debt reduction. Support compliance and audit activities (SOX, GxP, and other regulatory requirements), ensuring proper documentation, controls, and audit readiness. Maintain comprehensive system documentation, knowledge articles, and user guides to support adoption and operational excellence. Provide regular updates on project delivery, system health, and enhancement roadmaps to IT and business stakeholders. Stay current with industry trends across Finance, Procurement, and Commercial technology landscapes, identifying opportunities for innovation and value creation. Act as a trusted advisor to IT and business leaders on system capabilities, risks, vendor performance, and transformation initiatives. Requirements Bachelor’s ... (truncated, view full listing at source)