Research Associate, Genome Engineering

The Research Associate provides strong molecular biology and genome engineering support to build scalable IVT/circular vector production and genotyping workflows. This position serves as a key contributor to experimental execution, data generation, and workflow optimization across genome engineering programs. This role works with genome and cell engineering teams to develop, implement, and maintain workflows within the Genome Engineering Technology (GET) department. This position reports to the Associate Scientist, Genome Engineering. This position is based on-site in Dallas, TX. Relocation assistance is available. Duties and Responsibilities: Execute molecular cloning workflows, including circular vector design and assembly Perform in vitro transcription (IVT) to produce high-quality mRNA Conduct genomic DNA extraction, PCR, and NGS library preparation for genotyping Support optimization of genome editing workflows, including editor design and delivery strategies Maintain accurate experimental records in Benchling (ELN) Organize reagent inventories and track experimental materials Collaborate with cross-functional teams to support genome engineering projects Assist in troubleshooting and improving experimental protocols Required Skills and Abilities: Experience with molecular biology techniques such as PCR, DNA/RNA handling, and cloning Familiarity with genome editing technologies (e.g., CRISPR, Prime Editing) preferred Knowledge of IVT, RNA production, or NGS workflows is a plus Experience with automation systems or high-throughput workflows is a plus Proficiency with standard lab equipment and data recording tools (e.g., Benchling) Strong attention to detail and organizational skills Ability to communicate clearly and work collaboratively in a fast-paced environment Education and Experience: Bachelor’s or Master’s degree in Molecular Biology, Genetics, Bioengineering, or related field Prior relevant and hands-on laboratory research experience (industry or academic) Hands-on experience with molecular biology techniques strongly preferred What Colossal Offers Full-Time Employees: Medical, dental, and vision coverage Excellent paid time off and company holidays so you can rest and recharge Flexible spending accounts (FSA) Company matched 401k retirement plan Paid parental leave at 100% salary for up to 12 weeks Education reimbursement An opportunity to help us return the Earth to a healthier state The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices. Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal. Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive. EEO is the Law Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house. Colossal is proud to be named a Best Place to Work by BuiltIn for 4 years in a row across multiple categories in 2023, 2024, 2025, and 2026: #1 on the 50 Best Startups to Work For in Dallas in 2023! 100 Best Midsize Places to Work in Dallas in 2024 2025 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024, 2025, and 2026. Built In 2026 Award Lists Great Place to Work Certification Page Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, ... (truncated, view full listing at source)