Sr. Manager, Strategy & Execution

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three RD sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Sr. Manager, Strategy Execution as part of the Commercial team based in Bridgewater, NJ. Role Overview The Sr. Manager, Strategy Execution serves as a strategic thought partner and operational leader, driving execution of high-priority business initiatives and ensuring seamless integration across the Commercial organization. The role will report to SVP, Head of Commercial and will act as an extension of the SVP. The position will oversee strategic planning, 4DX execution, foster cross-functional alignment, and enable efficient operations across Sales, Marketing, Market Access, External Engagement, Commercial Assessment, and Commercial Operations. The ideal candidate brings a proven track record in leadership, strategic execution, project management, and operational excellence, with exceptional communication and collaboration skills. Key Responsibilities Manage and facilitate key leadership meetings, including Commercial Leadership Team sessions, Quarterly Business Reviews, and strategic planning forums. Partner with functional leaders across Sales, Marketing, Market Access, External Engagement, and Operations to drive alignment and execution of Carvykti’s commercial strategy. Ensure integration of commercial performance dashboards (4DX) and monitor organizational progress in collaboration with the PMO; contribute to vision-setting and prioritization of commercial initiatives. Foster a culture of transparency, collaboration, and engagement across the commercial organization. Track and manage SVP-assigned priorities and deliverables, ensuring timely completion and accountability. Identify operational efficiencies and implement solutions to enhance organizational effectiveness. Lead special projects and strategic initiatives requiring cross-functional collaboration and analysis of commercial performance. Interface with corporate functions including Finance, HR, IT, and Legal to ensure seamless integration and support for commercial priorities. Support ad hoc strategic analyses and opportunity assessments to inform commercial decision-making. Drive execution of the 4DX (Four Disciplines of Execution) roadmap, ensuring focus on Wildly Important Goals (WIGs), lead measures, and accountability through regular cadence reviews. Partner with the Commercial Culture Club to design and implement culture-building initiatives that reinforce engagement and high-performance behaviors. The authority to make decisions related to project execution, including timelines, milestones and resource allocation within budget. Requirements Bachelor's degree with 7+ years of industry experience and demonstrated leadership in project and/or operational management. Master degree preferred Creative, strategic thinking, operational effectiveness, and strong troubleshooting skills Strong holistic approach to working with groups of high-performance individuals. Able to pull the best from teams while at the same time being able to contribute and help synthesize. High EQ w ... (truncated, view full listing at source)