Job Description
<div class="content-intro"><p style="line-height: 1.2;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&amp;D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.</span></p>
<p style="line-height: 1.2;">&nbsp;</p>
<p style="line-height: 1.2;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson &amp; Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.</span></p>
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<p><span style="font-size: 12pt; font-family: arial, helvetica, sans-serif;">Legend Biotech is seeking<strong> Senior Scientist/Principal Scientist, Quantitative Pharmacology (Contractor)&nbsp;</strong>as part of the&nbsp;<strong>Research &amp; Early Development </strong>team based in <strong>Somerset, NJ.&nbsp;</strong></span></p>
<p><span style="font-size: 12pt; font-family: arial, helvetica, sans-serif;"><strong>Role Overview</strong></span></p>
<p class="drawer-body-p"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">The position seeks a highly motivated and experienced quantitative pharmacologist to lead modeling and simulation efforts in support of gene and cell therapy products, with a focus on QSP and popPK modeling (Prior cell and gene therapy experience preferred).</span></p>
<p class="drawer-body-p"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;"><strong>Contract Duration: </strong>12 Months</span></p>
<p><span style="font-size: 12pt; font-family: arial, helvetica, sans-serif;"><strong>Key Responsibilities</strong> &nbsp;</span></p>
<ul>
<li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Lead QSP and popPK modeling activities across preclinical and clinical development stages.</span></li>
<li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Play a pivotal role in shaping clinical pharmacology strategies, supporting regulatory submissions, and driving innovation in model-informed drug development (MIDD).</span></li>
<li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Develop and apply mechanistic models to understand disease pathways, drug mechanisms, and patient variability.</span></li>
<li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;& ... (truncated, view full listing at source)