Sr. Director, Head of GU Oncology Lifecycle Management

Natera is a global leader in cell-free DNA testing focused on changing the management of disease in reproductive health, oncology, and organ transplantation. Signatera is a personalized, tumor-informed test for molecular residual disease (MRD) assessment and surveillance monitoring in patients previously diagnosed with cancer. Signatera is covered by Medicare for colorectal cancer, muscle invasive bladder cancer, high-risk breast cancer, ovarian cancer, lung cancer, and immunotherapy response monitoring for any solid tumor. As the Head of GU Oncology Lifecycle Management, you will shape the vision and strategy for Natera’s oncology product portfolio in GU cancers. Your leadership will drive a cohesive, cross-functional approach—partnering with medical, sales, business development, and other key teams—to position our products effectively and address critical unmet needs in cancer care. Reporting directly to the VP of Oncology Lifecycle Management, you will own the GU disease area strategy, and make high-impact decisions to maximize the clinical and commercial success of our oncology solutions. PRIMARY RESPONSIBILITIES: Own the lifecycle planning and success of GU cancers , collaborating with cross-functional teams to develop and execute a strategic plan that drives usage, awareness, and advocacy across key stakeholders worldwide. Expand Signatera access across GU tumors – prioritize key indications, own evidence roadmaps, close evidence gaps and submit for coverage Establish tumor-specific goals to be owned by the lifecycle team and across functions. Serve as a critical member on clinical / medical teams, helping define and prioritize key indications while identifying and addressing evidence gaps. Monitor performance mitigate risks – In close partnership with Marketing team, track performance and deliver against GU commercial and medical goals, identifying potential issues / risks and implement mitigation strategies Serve as a critical member on commercial subteams, helping to maximize Natera potential by escalating and addressing critical barriers that limit commercial adoption. Maintain a deep expertise in the GU cancers space by integrating real-time customer insights, publications, data presentations, competitive and market intelligence. Shape the value proposition for Natera’s oncology products in collaboration with Medical Affairs and Commercial Marketing, leveraging clinical evidence and market dynamics. Regularly present strategic plans and progress to executive leadership. QUALIFICATIONS: Bachelor’s degree, Advanced degree preferred (MBA or PhD) GU oncology market experience strongly preferred 8-10 years experience in product marketing, market analytics at a pharmaceutical / biotech company Previous KOL management experience preferred Working knowledge of oncology molecular testing / biomarkers ~25% travel required (advisory boards, congresses, sales / marketing meetings, customer meetings) KNOWLEDGE, SKILLS, AND ABILITIES: Ability to lead without authority, influence and inspire individuals Proven strategic agility with an enterprise mindset and ability to operate with executive presence Ability to partner and collaborate across a broad range of internal and external partners Strong customer orientation and focus, particularly establishing thought leader relationships Proven ability to communicate the complex simply (biomarkers, multiple indications, etc.) Strong organizational / time management skills; manage and complete multiple projects PHYSICAL DEMANDS WORK ENVIRONMENT: Duties are typically performed in a remote home office setting. This position requires the ability to use a computer keyboard, communicate over the telephone/computer, and read printed material. Duties may require working outside normal working hours (evenings and weekends) at times. While the position may be based anywhere in the United States, availability during Pacific time hours is required. Travel req ... (truncated, view full listing at source)