Vice President, Laboratory Software Engineering
NateraUS RemotePosted 26 March 2026
Job Description
Vice President, Laboratory Software Engineering
Reports to: SVP, Laboratory Systems and Product Engineering Work Model: Remote (with periodic travel to San Carlos, CA and Austin, TX)
Position Summary
The Vice President of Laboratory Software Engineering is an enterprise executive role responsible for the strategy, modernization, and delivery of informatics platforms that power sample accessioning, order and sample tracking, and end-to-end workflow orchestration across both wet and dry laboratories.
This role leads an organization of approximately 200 people and supports multiple business units, including Oncology Minimal Residual Disease (MRD), Oncology Comprehensive Genomic Profiling (CGP), Early Cancer Detection (ECD), Women’s Health (WH), and Organ Health (OH).
Operating in a CLIA- and CAP-certified clinical laboratory environment with FDA-regulated diagnostics, the VP will lead the transformation of a fully homegrown informatics ecosystem. This leader is accountable for defining enterprise platform strategy, driving large-scale modernization, and making critical build-vs-buy decisions to ensure scalability, reliability, regulatory compliance, and operational excellence.
In the first 90 days , the VP is expected to build strong relationships with laboratory, product, engineering, quality, and regulatory stakeholders; develop a deep understanding of existing informatics platforms and laboratory workflows; assess organizational strengths and gaps; and establish credibility with laboratory users through direct engagement, including onsite interaction. The leader should also identify near-term risks and opportunities while defining clear principles for platform modernization.
Within the first year , the VP is expected to define and begin executing a multi-year enterprise informatics roadmap, make key architectural and build-vs-buy decisions, align the organization around standardized platforms, and demonstrate measurable improvements in scalability, reliability, and operational efficiency. Success will be reflected in stronger partnership with laboratory operations, improved readiness for regulatory audits, and tangible progress toward a modern, enterprise-grade informatics ecosystem that supports current and future business growth.
Key Responsibilities
Enterprise Informatics Strategy Platform Modernization
Define and own the enterprise laboratory informatics strategy spanning sample accessioning, order management, sample tracking, and workflow orchestration across wet labs, dry labs, and downstream data consumers.
Lead the modernization of a predominantly homegrown informatics landscape, including architectural redesign, platform consolidation, and technology standardization.
Drive strategic build-vs-buy decisions, including vendor evaluation, platform selection, and long-term ownership models.
Establish and execute a multi-year roadmap that supports enterprise growth, new product introductions, and evolving regulatory expectations.
Clinical Operations Enablement Scalability
Ensure informatics platforms reliably support high-throughput, mission-critical laboratory operations across Oncology, Women’s Health, and Organ Health portfolios.
Partner closely with laboratory operations, product, RD, quality, and regulatory teams to optimize workflows, increase automation, and reduce operational friction.
Enable rapid onboarding of new assays and laboratory workflows while maintaining system stability, data integrity, and compliance.
Define and track KPIs related to system performance, availability, throughput, and operational efficiency.
Leadership Organization Development
Lead, mentor, and scale a high-performing organization of approximately 200 professionals across laboratory applications engineering, workflow platforms, data systems, validation, and operations support.
Build strong leadership bench strength and succession plans across a geographically distributed organization.
Foster a culture of technical ... (truncated, view full listing at source)
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