Manager, Supply Chain Management

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values: *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. *MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: The Manager, Supply Chain Management is responsible for day‑to‑day operational execution of supply chain activities supporting Vaxcyte’s clinical, GMP, PPQ, and commercial readiness programs. This role focuses on tactical planning, execution, tracking, and issue resolution across materials, logistics, and external partners, ensuring smooth and compliant operations in support of manufacturing campaigns. The role works closely with the Associate Director, Supply Chain, who retains end‑to‑end strategic ownership across programs, while the Manager, Supply Chain Management ensures disciplined execution, follow‑through, and operational stability. Essential Functions: Operational Supply Chain Execution Execute approved supply chain strategies and plans across GMP, PPQ, and clinical/commercial readiness activities. Manage day‑to‑day material planning, ordering, and tracking to ensure on‑time availability aligned with manufacturing schedules. Support execution of supply activities across multiple programs, with a focus on operational readiness and delivery. Manage and coordinate Critical Raw Materials and Customer‑Supplied Materials provided to Lonza. Materials, Logistics Vendor Coordination Coordinate shipments and storage with the Logistics Team. Track material movements, inventories, and material status, proactively escalating risks or delays, particularly for Critical Raw Materials. Act as the primary operational interface between Supply Chain and Procurement / Buyer, ensuring alignment between ordered materials, delivery timelines, and campaign execution needs. CDMO External Partner Support Support operational interfaces with CDMOs, primarily Lonza. Participate in recurring Lonza‑related forums (e.g. VIBEX, MINT material ordering, allocation, and operational alignment meetings). Follow up on action items, timelines, and required documentation to enable smooth execution. Support deviation‑related activities by coordinating information flow between Supply Chain, Quality, and Operations. Tracking, Reporting Documentation Maintain operational trackers, dashboards, and status updates related to materials, shipments, and readiness. Own the accuracy and maintenance of campaign progression data, including OMP‑related tracking, ensuring consistency across Supply Chain, Manufacturing, and Lonza‑reported data. Support preparation of weekly and recurring campaign updates by providing validated execution‑level data. Issue Resolution Continuous Improvement Act as a first line of response for operational issues related to materials, logistics, and execution. Escalate issues with clear data, options, and recommendations to the Associate Director. Identify opportu ... (truncated, view full listing at source)