Scientist II/Senior Scientist CMO MSAT

<div class="content-intro"><p style="line-height: 1.2;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three RD sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.</span></p> <p style="line-height: 1.2;"> </p> <p style="line-height: 1.2;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.</span></p> <p style="line-height: 1.2;"> </p></div><p><span style="font-size: 12pt; font-family: arial, helvetica, sans-serif;">Legend Biotech is seeking a<strong> Scientist II/Senior Scientist CMO MSAT </strong>as part of the<strong> External Manufacturing</strong> team based in <strong>Raritan, NJ</strong>.</span></p> <p><span style="font-size: 12pt; font-family: arial, helvetica, sans-serif;"><strong>Role Overview</strong></span></p> <p>The position will be part of the CMO MSAT team driving the capacity ramp-up and supporting commercial manufacture of Carvykti at our external manufacture partners. He/she is part of an integrated virtual management team, working with our partner JNJ, to oversee the technical side of the CMO operation.</p> <p><span style="font-size: 12pt; font-family: arial, helvetica, sans-serif;"><strong>Key Responsibilities</strong></span></p> <ul> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Oversee and support CMO technical operations and routine manufacturing: including deviation investigations, change controls, process improvements and continuous process validation.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Serve as a technical Person-In-Plant (PIP) for commercial batches, including off-hours or weekend coverage when required.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Represent MSAT in internal and external cross-functional meetings, providing timely and structured updates on project status, technical risks and mitigation strategies.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Partner with Data Scientists to support monitoring manufacturing performance, identify and investigate out-of-trend critical process parameters (CPPs) in-process testing and critical quality attributes (CQAs).</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Collaborate with the global MSAT team to implement change controls and drive process improvement initiatives.</li> </ul> <p><span style="font-size: 12pt; font-family: arial, helvetica, sans-serif;"><strong>Requirements</strong></span></p> <ul> <li class="col-xs-12 no-horiz-padding" style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">BS/MS in a related technical discipline (Engineering, Biological Sciences, Pharmaceutical Sciences, etc.) with 5 years of experience in the industry or 3 years’ experience in cell therapy.</li> <li class="col-xs-12 no-horiz-padding" style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">CAR-T manufacturing and CMO oversight experience strongly preferred.</li> <li class="col-xs-12 no-horiz-padding" style="font-family: arial, helvetica, sans-serif; font-si ... (truncated, view full listing at source)