Senior Director, Field Strategy & Enablement

Xenon Pharmaceuticals
BostonPosted 27 March 2026

Tech Stack

Job Description

Senior Director, Field Strategy & Enablement Who We Are: Xenon Pharmaceuticals (NASDAQ:XENE https://www.nasdaq.com/market-activity/stocks/xene) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team. What We Do: We are advancing an exciting product pipeline https://xenon-pharma.com/pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we anticipate submitting a New Drug Application to the Food and Drug Administration in the third quarter of 2026. Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial. In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting, and continue to advance an early-stage pipeline of novel therapeutic candidates. In 2025, we initiated Phase 1 trials for XEN1701 (targeting Nav1.7) and XEN1120 (targeting Kv7). Nav1.7 and Kv7 are important pain targets, and data from these Phase 1 studies are expected in 2026 to support Phase 2 proof-of-concept studies in acute pain. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations. About the Role: The Senior Director, Field Strategy & Enablement will be responsible for driving the execution of strategy and operational excellence across Sales & Marketing, coordinating with leadership to define priorities, translate growth strategies into actionable plans, and ensure accountability for initiatives. Reporting to the Senior Vice President, Sales & Marketing, this role leads annual and quarterly planning, manages the operating cadence, and partners with cross-functional teams to optimize pipeline health, forecasting, and revenue performance. Additional responsibilities include developing executive dashboards for data-driven decisions, identifying and resolving process gaps, organizing national and regional meetings, leading sales training and enablement, and measuring training effectiveness. The Senior Director will recruit and develop team members, oversee budget planning, uphold company policies, and support both short- and long-term objectives, with some international travel required. This position will be based out of “Boston, MA, USA in our Needham office”. We will consider remote locations for exceptional candidates. Hybrid positions require a minimum of two onsite days per week. RESPONSIBILITIES: - Drive strategy execution, operational excellence, and enablement across Sales & Marketing - Coordinate, advance and implement field excellence while partnering with Sales & Marketing leadership - Partner with Sales and Marketing leadership to define priorities, drive execution, and ensure accountability across initiatives - Translate go-to-market and growth strategies into operating plans, milestones, and KPIs - Lead annual and quarterly planning for Sales & ... (truncated, view full listing at source)
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