Scientist, Disease Modeling and Phenotyping

About Synapticure As a patient and caregiver-founded company, Synapticure provides instant access to expert neurologists, cutting-edge treatments and trials, and wraparound care coordination and behavioral health support in all 50 states through a virtual care platform. Partnering with providers and health plans, including CMS' new GUIDE dementia care model, Synapticure is dedicated to transforming the lives of millions of individuals and their families living with neurodegenerative diseases like Alzheimer’s, Parkinson’s, and ALS. The Role As part of building the next generation of neurodegenerative care, Synapticure is investing in cutting-edge biological platforms to understand and treat ALS, FTD, and related diseases at the cellular level. We are developing a novel patient-derived disease modeling platform using in vitro systems to advance our ability to screen, diagnose, and develop therapeutics tailored to patient-specific biology. Our initial focus is ALS and FTD, but our long-term vision includes applications across a wide spectrum of neurodegenerative disorders. We are seeking a Scientist, Disease Modeling and Phenotyping who thrives at the intersection of hands-on laboratory work and computational biology. In this full-time, in-person role based in Philadelphia, PA, you will lead the development of high-throughput iPSC-based cell models and apply phenotypic screening approaches using advanced imaging, transcriptomics, and biochemical assays. Your work will directly support the discovery and advancement of new diagnostics and therapeutics for patients living with neurodegenerative diseases. You’ll play a critical role in both the wet lab and analytical domains;developing screening protocols, executing experiments, and helping analyze and interpret complex datasets. This is a unique opportunity to contribute directly to the future of neurodegenerative disease research while collaborating with a cross-disciplinary team of biologists, neuroscientists, clinicians, engineers, and data scientists. If you're motivated by science with impact, this role offers the chance to make a real difference in patients’ lives.