Senior Scientist, Immunology – Foster City, CA (San Francisco Bay Area)

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Overview Hundreds of millions of human genomes and exomes are expected to be sequenced over the next decade, driven by steady innovations in sequencing technologies pioneered by Illumina. The enormous quantities of genomic data being generated by Illumina in collaboration with our partners worldwide represents a major opportunity to develop novel data-driven and artificial intelligence methods to extract clinically actionable information from the genome, and apply it towards improving human health. Our Exceptional Multi-disciplinary Team Is Unlocking The Power Of The Genome Illumina is the worldwide leader in genome sequencing and deriving insights on the impact of the human genome on health and disease.  We are currently seeking a highly motivated and talented experimental scientist to lead a multi-disciplinary project working on perturb-seq in primary human immune cells, and experimental validation of novel targets directly identified from human genetics. Illumina’s leadership position in the generation and analysis of human genetic data enables us to pursue a unique human genetics-first approach to target discovery, supported by a multidisciplinary team of dedicated experimental scientists, statistical geneticists, and deep learning engineers working collaboratively to validate therapeutic hypotheses. We are looking for a highly innovative wet lab scientist to design, plan, and execute experiments in the laboratory in support of these early discovery efforts.  The successful candidate is expected to pursue novel approaches to study a broad range of different disease indications using high throughput functional genomics strategies, with a focus on identification and validation of therapeutic targets and next-generation biomarkers. Education requirements Ph.D in immunology, cell biology, molecular biology, bioengineering, or similar degree Required Experience and Skills Extensive expertise with immunology and molecular biology techniques, with particular emphasis on development of high-throughput sequencing assays, single cell sequencing, CRISPR, target identification, and target validation. Strong record of technical proficiency, innovation, and scientific rigor as demonstrated by publication in high-quality scientific journals. Roles and Responsibilities of the Position Develop the techniques and systems for running high-throughput sequencing experiments for target identification and validation. Design, develop and validate quantitative cellular assays to credential novel targets. Work closely with academic and clinical collaborators to integrate innovative biology with data from large-scale human genetics and high throughput sequencing assays to develop new target hypotheses. Present results at scientific meetings and publish in peer-reviewed scientific journals. About Us The role is based at the Illumina Foster City campus, our purpose-built facility centrally located in the San Francisco Bay Area, between San Francisco and Silicon Valley. At Illumina, you can expect a highly competitive salary accompanied by a market-leading benefits package. You will be part of the global leader in the DNA sequencing industry, where you will find robust growth opportunities and career development. Our team members are bright, energetic, and ... (truncated, view full listing at source)