Senior Bioinformatics Scientist

Illumina
US - California - San Diego$129k – $194kPosted 7 April 2026

Job Description

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Why Us We are a multi-disciplinary and multinational team dedicated to supporting genomics researchers in making discoveries that change the world. Our algorithms are integral to DRAGEN, Illumina’s software platform for analyzing high-throughput sequencing data. This group is focused on bioinformatics support for clinical products, ensuring that customers receive the best possible experience and outcomes from our technologies. Why You We know the importance of your role and offer you a collaborative and supportive environment in which you are actively encouraged to develop your skills and knowledge. Illumina's mission is to improve human health by unlocking the power of the genome - if that inspires you, let's talk. If you are excited as we are about enabling customers to get the best out of the product and solving complex issues working with different teams. You will be part of a culture fueled by innovation, collaboration, and openness. To be successful as a Senior Bioinformatics Scientist, you will need a background in bioinformatics with a particular focus on analytical problem solving, data visualization and good communication skills. A consummate scientific background in at least two of Genomics, Statistics, Next Generation Sequencing, and/or High-Performance Computing will be key to your success. This role may be performed in the US remote. The Role The Senior Bioinformatics Scientist will drive the development of innovative genomics solutions used to support oncology treatment decisions using panels/amplicon sequencing. The primary functions of this position will be to design and conduct data analysis of development studies to demonstrate that our assays and algorithms meet performance requirements across different platforms, support assay development, and testing software implementations. Responsibilities: In collaboration with our experimental assay, systems integration, and bioinformatics teams, design and analyze experiments to support existing or new Illumina oncology assays. Perform validation and verification for clinical genomic products Provide technical guidance to internal and external collaborators. Participate in cross functional assay and algorithm R&D teams Effectively communicate plans and results across functions Requirements: PhD in bioinformatics, computation biology, statistics, math or related field Experience with common bioinformatics methods, and NGS data analysis Typically requires a minimum of 5 years of related experience with a Bachelor’s degree; or 3 years and a Master’s degree; or a PhD without experience; or equivalent work experience Proficiency in Linux for bioinformatics software development and data processing Familiarity in programming languages such as Python or R Good communication skills to contribute to cross functional project teams and work with stakeholders. Flexibility to work in a dynamic environment and adapt to new technologies and methodologies Experience in oncology products as well as with NGS assay teams is considered advantageous. #LI-REMOTE #LI-HYBRID The estimated base salary range for the Senior Bioinformatics Scientist role based in the United States of America is: $129,400 - $194,000. Should the level or location of the role change during the hiring process, the ... (truncated, view full listing at source)
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