Senior Software Engineer (Primary Analysis)
IlluminaUS - California - San Diego$129k – $194kPosted 7 April 2026
Job Description
What if the work you did every day could impact the lives of people you know? Or all of humanity?
At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.
Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.
What if the work you did everyday could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, can make a difference. Surrounded by extraordinary people, inspiring leaders, and world-changing projects, you will do more and become more than you ever thought possible.
We are searching for a software engineers who is ready to join us in this important mission.
Illumina’s Primary Analysis team specializes in designing algorithms and developing software to detect genomic data from signals contained within images. Implementation challenges include managing parallel tasks, optimizing memory accesses, and improving the speed and accuracy of genomic base calling. We develop methods to address these challenges by focusing on high reliability, speed, and completeness of results. We are seeking an exceptional individual to join our team in developing analysis solutions for use by researchers and clinicians worldwide.
Responsibilities:
Define software architecture solutions for our high-performance signal processing pipelines
Design, develop, debug, and integrate C/C software on Linux for multi-threaded applications
Optimize and accelerate software executed on Illumina instruments
Closely interact with the bioinformatics team, instrument design team, test and quality teams
Collaborate in an agile environment to maintain high quality software against established processes
Maintain awareness of industry trends and evaluate applicability of new software and hardware technologies to platform development efforts
Provide technical leadership where needed
Requirements:
Extensive knowledge and experience with C/C, Java or C#
Experience in multi-threading, and memory management techniques
Proficient with tools for software debugging and troubleshooting (GDB, etc.)
Proficient with tools for software performance analysis and optimization
Proficient with source control management repositories (such as GIT, SVN, etc.)
Extensive experience writing high quality unit tests against mock objects
Good understanding of object-oriented analysis and design
Strong problem-solving skills
Desired:
Extensive knowledge and experience in developing software for real-time systems
Experience with image processing algorithms and techniques
Experience with time-series analysis and interpretation of temporal data
Experience with Python and Python visualization libraries
Be customer-focused, team-oriented, and motivated, taking ownership of assigned tasks
Have proven ability to self-manage, as well as manage interdisciplinary relationships
Have proven verbal and written communication skills
Education & Experience:
BS/MS in Computer Science, EE, Bioinformatics, or related field
5 years of professional software development experience
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The estimated base salary range for the Senior Software Engineer (Primary Analysis) role based in the United States of Ameri ... (truncated, view full listing at source)
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