Director, IT SAP Finance/Commercial

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Location San Diego, CA Strong onsite presence required. This is not a remote role. Position Summary We are seeking a strategic, results-driven Director, IT SAP Finance/Commercial to own the delivery, operations, and evolution of our SAP Finance and Commercial landscape (Finance plus Order-to-Cash/Commercial capabilities) within a complex global environment. In this senior leadership role, you will be accountable for end-to-end value realization across the S/4HANA transformation and ongoing product roadmap—balancing deep domain expertise with executive partnership, people leadership, vendor/portfolio management, and budget accountability. You will serve as a primary liaison between IT and Finance/Commercial leadership, ensuring our SAP ecosystem enables growth, compliance, and scalable global operations. Responsibilities Strategic Leadership: Define and execute the multi-year roadmap for SAP Finance and Commercial (e.g., Record-to-Report, Procure-to-Pay, Order-to-Cash), aligning priorities to enterprise strategy, transformation milestones, and measurable business outcomes. Organization & People Leadership: Build and lead a high-performing SAP Finance/Commercial organization (internal teams and partners). Set the operating model, develop leadership bench strength, manage capacity planning, and drive a culture of accountability and continuous improvement. Executive Stakeholder Partnership: Act as a trusted advisor to CFO/Finance leadership and Commercial business leaders. Translate complex technology strategy into clear business value, influence investment decisions, and drive alignment across regions and functions. Portfolio, Program & Delivery Governance: Own the delivery portfolio across SAP Finance and Commercial products (projects, enhancements, and run). Establish governance, KPIs/OKRs, and controls to ensure delivery predictability, quality, and adherence to enterprise architecture standards. Budget & Vendor/Partner Management: Own the SAP Finance/Commercial budget (run and change), including licensing, systems integrators, AMS, and niche vendors. Lead SOW/MSA negotiations, manage performance to SLAs, and ensure clear ROI and value delivery. Risk, Controls & Compliance: Own the risk and controls posture for Finance/Commercial IT, ensuring designs and operations meet SOX, audit requirements, GDPR, and local statutory needs—including revenue, pricing, and order management control points. Change Management & Adoption: Partner with Business Transformation and OCM leaders to drive global deployment readiness, training strategy, and sustained adoption across Finance and Commercial user communities. Architecture & Integration Leadership: Lead design authority to resolve complex cross-domain decisions and ensure end-to-end integrity across SAP Finance, SAP Commercial (e.g., SD), and adjacent platforms (e.g., CRM, eCommerce, tax, middleware, data/analytics). Qualifications Education: Bachelor’s degree in Finance, IT, or related field; MBA or Master’s degree strongly preferred. Experience: Minimum 18 years in SAP Finance and/or Commercial domains, with at least 10 years leading teams and large, cross-functional programs. Transformation Track Record: Proven experience leading multiple large-scale, global SAP transformations (S/4HANA prefe ... (truncated, view full listing at source)