Senior Manager/Associate Director, Commercial & Medical Information Systems

Senior Manager/Associate Director, Commercial & Medical Information Systems Who We Are: Xenon Pharmaceuticals (NASDAQ:XENE https://www.nasdaq.com/market-activity/stocks/xene) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team. What We Do: We are advancing an exciting product pipeline https://xenon-pharma.com/pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we anticipate submitting a New Drug Application to the Food and Drug Administration in the third quarter of 2026. Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial. In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting, and continue to advance an early-stage pipeline of novel therapeutic candidates. In 2025, we initiated Phase 1 trials for XEN1701 (targeting Nav1.7) and XEN1120 (targeting Kv7). Nav1.7 and Kv7 are important pain targets, and data from these Phase 1 studies are expected in 2026 to support Phase 2 proof-of-concept studies in acute pain. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations. About The Role We are seeking a Senior Manager/Associate Director, Commercial & Medical Information Systems, to join our Information Technology (IT) team. The Senior Manager/Associate Director, Commercial & Medical Information System will partner with leaders across Commercial and Medical, and other functions as needed to drive adoption, operations, and ongoing enhancements to the IT systems and support the implementation and management of the Commercial and Medical IT system. The ideal candidate has a strong understanding of Commercial and Medical business processes, with prior experience with the Veeva suite of products, Commercia Data Warehouse, and other key Commercial and Medical IT systems for current and future needs. The position reports to the Director, Commercial & Medical Information Systems and will be based out of Boston, MA, USA in our Needham office. The level of the position will be commensurate with the candidate’s education and industry experience. Hybrid positions require a minimum of two onsite days per week. RESPONSIBILITIES: - Partner with functional stakeholders and vendors to build new solutions supporting the Commercial and Medical functions, including integrations between systems and between Xenon and key service providers. - Author, review, and approve applicable SDLC deliverables, and coordinate assurance and other testing activities. - Develop, review, and approve procedures defining System Administration activities. - Collaborate with Xenon’s Architecture Review Board to ensure the system design is consistent with company standards for security, infrastructure, and data architecture. - Manage and execute day-to- day ... (truncated, view full listing at source)