Sr. Operational Excellence Engineer

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three RD sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Sr. Operational Excellence Engineer as part of the Technical Operations team based in Raritan, NJ. Role Overview This position will be responsible for providing operational excellence continuous improvement support to the cGMP Clinical and Commercial Cell Therapy Manufacturing plant. This individual will lead continuous improvement initiatives with various site functions to support of personalized cell therapy production through safe and compliant manufacturing operations according to cGMP requirements. The individual will be responsible for owning, driving and delivering cost saving and/or efficiency improvements, ensuring alignment in support of the overall objectives and priorities of the plant. The role will require proven lean leadership and expertise that drives disciplined problem solving and effective continuous improvement via communication, coordination and collaboration across relevant cross functional groups to establish a strong culture that enables robust production, testing and release of product to patients. Key Responsibilities Owns, plans, leads, develops, provides expertise, trains, coaches, drives and executes against an effective, holistic continuous improvement and problem solving program to improve safety, compliance, cost, process stability building quality and efficiency into processes to improve lead times and reliability in delivery to patients. Executes the defined continuous improvement program through the use of lean and six sigma manufacturing methodologies such as DMAIC, standard and standardized work, metrics, visual tools, PDCA, Kanban, pull systems, SMED, pareto, FMEA, A3 thinking, time studies, poke yoke, process mapping and others. Responsible for identifying and reporting progress updates to various levels of leadership and key stakeholders. Leads, facilitates and teaches others to lead and participate in kaizen events and increase continuous improvement skills. Facilitates in value steam analysis and hoshin planning events. Mentors selected plant team members to become yellow or green belts. Performs voice of the customer (VOC) via process capability and defect elimination. Applies and teaches change management methodology in all aspects of the plant operational excellence efforts. Routinely engages functional plant leaders to develop a continuous improvement culture. With respect to the coaching of others to upskill, you have the authority to make decisions regarding approach and methodology. With respect to cost savings initiatives, have the authority to engage with appropriate departments to define the problem, map out the current state and the future state, obtain alignment, and request resources from PMO. PMO requests should be reviewed by direct supervision prior to submission. With respect to larger continuous improvement system implementation and improvements, you have the authority to engage with functions as needed and develop continuous improvement system implementation approach. Strategic sh ... (truncated, view full listing at source)