Vice President, Clinical Development

Septerna is a biotechnology company based in South San Francisco, CA on a mission to develop life-changing medicines for patients with the vision to become the industry-leading G protein-coupled receptor (GPCR)-focused drug discovery company. The company’s Native Complex Platform™ recapitulates GPCRs with their native structure, function, and dynamics outside of the cellular context. This approach enables novel access to modern structural and screening technologies used in industrial-scale drug discovery for the entire class of GPCRs. Septerna has an emerging pipeline of GPCR-targeted small molecule programs with potential for growth to target many GPCRs that have been undruggable and unexploited to date. We are excited to expand our multidisciplinary team of individuals focused on creating revolutionary medicines to address the unmet needs of patients. At Septerna we strive to embrace diversity of thought, expertise, and background through collaboration. To join our ambitious team, be prepared to bring your real self to work every day; grow and learn from a talented team of drug hunters, scientists, and business professionals; and contribute your passion, creativity, and energy to accomplish our mission. We share a fearless pursuit of ground-breaking innovations and cultivate an environment where our employees succeed by learning from each other and working as a team. We are committed to the development of meaningful therapeutics for patients with indications of high unmet need. This is a tremendous opportunity to work with talented individuals on the frontlines of therapeutic discovery and development. You will directly help move therapies through preclinical research, positioning them for success in the clinic. The successful candidate will add their passion, unique talents, and expertise to a dynamic team motivated to discover new disease-modifying therapeutics for patients in a fast-paced environment. For more information see: www.septerna.com . About The Role Septerna has an exciting new opportunity to join the team as a Vice President, Clinical Development, reporting to the Chief Medical Officer. The VP, Clinical Development will join the Senior Leadership Team and provide key strategic leadership for clinical development strategy, planning, and tactical implementation for all clinical development functions. This position will also serve as the Product Development Team Leader (PDTL) for one or more of Septerna’s clinical stage programs. The PDTL is responsible for product strategy and the design and successful cross-functional implementation of the development plan. S/he will also participate in regulatory interactions and contribute to building relationships with KOLs. Ability to bridge clinical, scientific, and business needs with the aptitude to translate and align business and scientific goals and objectives. Must be a dynamic leader with outstanding strategic, communication, and collaboration skills. Responsibilities Enterprise leader of program strategy, collaborating in a matrixed working environment with clinical operations, regulatory, clinical pharmacology, research, CMC, and other functions to ensure the success of drug development programs. Work with key internal and external stakeholders to lead the design and implementation of robust CDPs and integrated development plans to achieve the desired target product profile. Guide the development team(s) with aggressive, creative, but realistic approaches to drug development. Direct and design fit-for-purpose clinical trials across all phases in drug development; design and draft protocol synopses, clinical trial protocols, amendments, and supporting documents. Contribute to IBs, regulatory documents, CSRs, and publications associated with clinical trials. Provide medical oversight of multiple clinical studies and provide medical input and guidance on scientific, clinical and safety monitoring issues. Be accountable via collaboration across functions ... (truncated, view full listing at source)