Senior Internal Auditor II - IT (San Diego/Hybrid)
IlluminaUS - California - San Diego$108k – $162kPosted 28 April 2026
Job Description
What if the work you did every day could impact the lives of people you know? Or all of humanity?
At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.
Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.
Position Summary:
The Senior Internal Auditor II – IT is a key member of Illumina’s Internal Audit function and reports to the Associate Director, Internal Audit – IT. This role supports both the planning and execution of the Company’s SOX compliance program and IT advisory engagements for system implementations.
The successful candidate will evaluate the effectiveness of internal controls and risk management practices, partner closely with cross-functional stakeholders, and provide independent and objective IT-related advisory services. This role requires the ability to quickly and fully understand end-to-end business processes, the capacity to clearly and succinctly communicate technology, financial and operational risks to management, and strong technical and auditing expertise.
This position offers a pathway to develop into a future IT, Finance and/or business leader while working in a fast-paced, collaborative environment.
*This is a full-time role, Monday through Friday, with an expectation of at least one day in-office and additional on-site presence when business needs require. The individual must reside in the San Diego area and be able to commute to our corporate offices. Relocation assistance is available and should be completed within a three (3) month period or a mutually agreed upon time.
Key Responsibilities:
Lead and/or execute assigned components of the Company’s SOX compliance program, including risk assessment, scoping, walkthroughs, and testing of IT general and application controls
Collaborate with external auditors to support SOX-related assurance activities and SEC reporting timelines
Independently evaluate control deficiencies, perform root cause analysis, and partner with control owners in their design and implementation of remediation actions, through to closure
Review and maintain high-quality SOX documentation, including narratives, process flowcharts, control descriptions, and risk and control matrices
Support periodic updates to control design to improve efficiency, effectiveness, and scalability
Build strong, trusted relationships with cross-functional partners at various levels of management
Maintain Internal Audit systems and tools infrastructure and implement departmental technology initiatives
Assist with and/or lead departmental initiatives, special projects, and Finance-wide initiatives as needed
All About You:
You are a business-and tech-savvy audit professional with strong analytical and critical thinking skills. You thrive in a fast-paced environment, adapt quickly to change, and take pride in delivering high-quality work. You communicate clearly and confidently, can work independently or as part of a team, and build effective relationships across the organization.
Requirements:
Typically requires a minimum of 8 years of progressive audit experience in a public accounting firm and/or multinational public company with a bachelor’s degree; or 6 years and a master’s degree; or a PhD with 3 years of experience; or equivalent experience.
Experience designing, monitoring, and evaluating internal controls in a multinational environment
Knowledge of IT General Controls, Application Controls, cybersecurity, and ERP environments (SAP preferred)
Experience working in life sciences, biotech, technolog ... (truncated, view full listing at source)
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