Sr. Bioprocess Engineer

Culture Biosciences
South San Francisco, CA$110k – $145kPosted 1 April 2026

Job Description

About Us: Culture’s mission is to simplify and accelerate bioprocess development to enable our customers to bring their biopharmaceutical products to market faster. With a focus on upstream cell culture process development, Culture has developed a unique platform that merges products, services and data management that can be applied to mammalian, microbial and viral vector production processes. This platform enables high-throughput process development projects to be rapidly and seamlessly executed directly by our customers in their own facilities, in our service laboratories, or both, all driven by our cloud-connected web application, accessible from anywhere, for designing, managing and analyzing experiments. At Culture, we combine our passions for biomanufacturing, engineering, and operations to build new solutions that make bioprocess development faster. We value curiosity, communication, collaboration, a customer focused mindset and a drive for results. The Opportunity: The Sr. Bioprocess Engineer is a senior technical role combining deep bioprocess expertise with client delivery, operational execution, and platform development. Following commercial engagement, you become a key technical partner for clients throughout the lifecycle of their program. You will own the technical execution of complex, multi-phase client initiatives including technical transfer, process development and optimization, and experimental campaigns across microbial fermentation, mammalian cell culture, and viral vector modalities. Beyond client work, you will also lead and contribute to internal RD projects that advance our platform capabilities and drive innovation across the organization. In this role, you will translate customer process requirements into structured execution plans, coordinate cross-functional teams, manage risk, and ensure delivery against scope, timeline, and quality expectations. You will work closely with clients to refine experimental strategy, anticipate technical challenges, interpret data, and guide decision-making. What sets this role apart is your hands-on technical involvement: you will directly develop and optimize bioprocesses, write and adapt fermentation control logic, troubleshoot bioreactor systems, and perform in-depth data analysis to drive scientific insights. You will operate with high autonomy and accountability, balancing customer needs, operational constraints, RD priorities, and platform strategy. This role requires deep bioprocess expertise combined with strong technical execution and project leadership to drive repeatable, scalable, and predictable outcomes. Your impact will be measured not only by successful technical execution, but by long-term client trust, program expansion, operational robustness, and the scalable systems and processes you help build. What You’ll Do: Serve as a primary technical point of contact for assigned clients, owning the technical relationship and program delivery from onboarding through completion. Build trusted partnerships and operate as a strategic thought partner, advising on experimental design, process decisions, risk mitigation, and scale-up considerations. Translate client process requirements into structured, executable program plans that define milestones, dependencies, resources, and quality standards. Align and coordinate cross-functional teams across Bio Ops and Innovation, Product, Software, and Hardware to ensure seamless execution and predictable outcomes. Oversee and directly execute complex technical transfers and experimental campaigns, ensuring scientific rigor, reproducibility, and operational readiness. Develop, optimize, and troubleshoot upstream bioprocesses hands-on, including bioreactor setup, operation, sampling, and process parameter optimization. Write, adapt, and maintain bioprocess control logic scripts in Python, including fermentation control sequences and automation workflows. Perform in-depth analysis of experimental and bio ... (truncated, view full listing at source)
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