Systems Engineer II

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK. For patients, for each other, and for the future of science, we’re in. Are you? About the Role: As Systems Engineer II, you will be a hands-on technical leader responsible for architecting, engineering, and operating enterprise-scale infrastructure across on-prem datacenters, virtual platforms, and cloud environments (AWS/GCP/Azure). You will manage the full lifecycle of compute, server provisioning, networking, storage, core services, monitoring, automation, security, and disaster recovery. You will also modernize legacy systems, drive automation-first operations, and deliver resilient, scalable, and secure infrastructure to support global business operations. What You'll Do: In this role, you'll have the opportunity to design, architect, and implement infrastructure solutions spanning on-premises datacenters, virtualized environments, and cloud platforms (AWS, GCP, Azure). You will also: Modernize compute, storage, and network services to improve reliability, performance, scalability, and security. Create high-quality architecture diagrams, technical specifications, and system design documentation. Lead end-to-end server provisioning and deprovisioning for Windows and Linux platforms. Integrate server provisioning and lifecycle tasks with ServiceNow automation and catalog workflows. Install, configure, and maintain physical and virtual servers, ensuring consistent standards and optimized performance. Build automation for server builds, configuration, patching, drift detection, and lifecycle workflows using PowerShell, Python, Terraform, or Ansible. Manage compute workloads across on-prem, virtual, and cloud environments, ensuring high performance and availability. Conduct capacity planning, performance tuning, and lifecycle governance across compute platforms. Support hybrid workload strategies aligned with business and application requirements. Manage hybrid storage environments (NetApp, SAN, NAS), replication, and disaster recovery configurations. Collaborate closely with Cybersecurity to reinforce hardening, vulnerability remediation, identity hygiene, and logging practices. Enhance monitoring and alerting across infrastructure platforms to ensure proactive detection and response. Contribute to disaster recovery planning, runbook creation, tabletop exercises, and failover testing. Who You Are: You have a minimum of a Bachelor’s degree in Computer Science, Information Technology or Engineering and/or 8 years of equivalent work experience in Systems Engineering or Infrastructure Architecture, including at least 3–5 years working with compute platforms, and datacenter environments. You are or you have: Proven track record of driving change, innovation, automation, and process excellence in fast-paced, highly regulated environments. Strong hands-on experience across compute platforms, including Windows Server, Linux (Ubuntu/Red Hat), virtualization, storage, and networking.  Knowledge of golden images. Experience managing compute in on-prem datacenters, virtual environments (VMware/Hyper-V), and cloud platforms (AWS, GCP, Azure). Advanced scripting and automation capabilities using PowerShell and Python, and experience with Infrastructure-as-Code tools such as Terraform or Ansible. Functional understanding of Directory Services (Active Directory, Azure AD/Entra ID, LDAP), as well as core Internet protocols including DNS ... (truncated, view full listing at source)