Senior Manager, R&D

POSITION SUMMARY: Natera is seeking an experienced Senior Manager, RD , to join the Oncology Product Development team. This role will lead development and optimization of NGS-based oncology diagnostic assays and support product lifecycle management post-launch. The ideal candidate will drive cross-functional initiatives, provide strong technical leadership, and partner with Operations to ensure robust and scalable product performance. PRIMARY RESPONSIBILITIES: Lead and execute technical development of NGS-based oncology assays, including project planning, execution, and cross-functional coordination Contribute to assay development from feasibility through verification and validation in a regulated (CLIA) environment Collaborate cross-functionally with Research, Informatics, Stats, Software, Regulatory, Quality, and Commercial teams to support product development and launch Support post-launch activities, including process improvements, troubleshooting, and collaboration with Operations for commercialized assays Prepare and review technical documentation, including study protocols, reports, and validation documentation, to support product development and regulatory compliance Manage and mentor team members Perform and guide data analysis using statistical tools QUALIFICATIONS: PhD in Molecular Biology or a related field with 6+ years of industry experience, or BS/MS with 8+ years of relevant biotech industry experience, including at least 2 years of management experience Experience in NGS-based assay development in a regulated environment (CLIA experience preferred) Familiarity with CLIA laboratory workflows and assay implementation in a production setting Demonstrated experience leading projects and collaborating cross-functionally; prior people management experience preferred Experience with high-throughput workflows or automation is a plus KNOWLEDGE, SKILLS, AND ABILITIES: Technical expertise in oncology diagnostics and NGS technologies Strong problem-solving and analytical thinking Technical writing and documentation skills in a regulated environment Understanding of regulatory requirements and design control processes in a regulated environment (e.g., LDT, CAP/CLIA, product development lifecycle, change management) Strong cross-functional collaboration, communication, and interpersonal skills with the ability to build effective working relationships Team leadership and development Compensation Total Rewards This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations. This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including: Annual performance incentive bonus Long-term equity awards Comprehensive health benefits (medical, dental, vision) 401(k) with company match Generous paid time off and company holidays Additional wellness and work-life benefits Compensation Range $157,400 $196,800 USD OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits - Employee benefits include com ... (truncated, view full listing at source)